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Thyroid nodules

The prevalence of thyroid nodules is very high in the general population, as the probability of finding a nodule by palpation is approximately 5%, a probability that reaches 68% when it comes to finding an occult nodule by ultrasound. 90% of nodules are benign and 95% are asymptomatic (5% may be associated with compressive local symptoms or thyroid dysfunction). Ninety percent of nodules are benign and 95% are asymptomatic (5% may be associated with compressive local symptoms or thyroid dysfunction). Approximately half of the patients with nodular thyroid disease have a single nodule. The diagnostic problem in the single thyroid nodule is to establish its benign or malignant nature. Risk factors for malignancy include a history of head and neck irradiation, exposure to ionizing radiation in childhood or adolescence, family history of thyroid cancer or hereditary syndromes associated with thyroid cancer, and rapid nodule growth or laryngeal paralysis.